I'm using bowtie2(version 2.1.0) to map two paired end fastq files, each ~13GB in size.
bowtie2 -p 30 --phred33 --local --sensitive -x ref_index -1 forward_reads.fastq -2 reverse_reads.fastq -S out.sam
It's running fine until it generates out.sam file 13.2GB and then throwing error
bowtie2-align died with signal 11 (SEGV) (core dumped).
Is this some memory problem? I am running on system with 32cores and 256GB of RAM.
Any help would be appreciated