Question: How to statistically test significance of molecular convergence in two unrelated lineages
gravatar for ishengomae
3.3 years ago by
Tanzania, United Republic Of
ishengomae100 wrote:

Hi Biostars,

This question is exactly what I need, How to test for convergent/parallel evolution in a group of homologous proteins?, but surprisingly, it hasn't received any response for over two years.

I'm at a point where I want to test whether convergent changes between the two unrelated lineages are random or not. This paper kind of established the method: Zhang, Jianzhi, and Sudhir Kumar. "Detection of convergent and parallel evolution at the amino acid sequence level." Molecular Biology and Evolution 14.5 (1997): 527-536.

Is there an R package that could make test for significance of molecular convergence rather straightforward?

Thanks all and look forward your responses.

ADD COMMENTlink modified 3.3 years ago by ddiez1.8k • written 3.3 years ago by ishengomae100
gravatar for ddiez
3.3 years ago by
ddiez1.8k wrote:

Have you taken a look in the Phylogenetics task view at CRAN? There is a package, convevol, that might be what you are looking for, as it is described as:

Quantifies and assesses the significance of convergent evolution.

There might be other (I guess many), non-R options.

ADD COMMENTlink written 3.3 years ago by ddiez1.8k

This looks like what I want. Thanks.

ADD REPLYlink written 3.3 years ago by ishengomae100
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1018 users visited in the last hour