Question: GWAS Meta analysis
gravatar for alessandrotestori7
3.6 years ago by
alessandrotestori7390 wrote:

Hi everybody. I am doing a sort of meta-analysis between two different GWAS datasets in order to see whether particular SNPs or sets of SNPs contribute to both pathological conditions. I am currently using METAL with the inverse variance-based method. However, when a SNP is very significantly associated to a disease and not to the other, the meta-analysis p-value is still very significant and this spoils the final result. What can I do to avoid such inconvenience? Please let me know. Thanks. Cheers!

meta-analysis gwas • 1.3k views
ADD COMMENTlink written 3.6 years ago by alessandrotestori7390

Any hint? Please let me know.

ADD REPLYlink written 3.5 years ago by alessandrotestori7390
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