Question: Looking for a Transcriptome meta-analysis algorithm
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gravatar for spacemorrissey
2.9 years ago by
United States
spacemorrissey230 wrote:

What algorithms would you suggest for performing a transcriptome meta-analysis? I have data from more than 20 GEO data sets. I have counted the number of experiments in which a given gene is differentially expressed, and I’ve normalized the data and used both supervised and unsupervised clustering on it. I’m trying to find an algorithm to combine the 20 different p-values, fold changes, or both. Thanks.

rna-seq • 861 views
ADD COMMENTlink written 2.9 years ago by spacemorrissey230

Hi dear spacemorrissey You can use www.networkanalyst.ca , to combine p-values obtained from different independent studies. It offers you a variety of methods e.g fisher method as a more sensitive method to combine your results. Best

ADD REPLYlink written 2.9 years ago by Shamim Sarhadi210
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