Question: continuos covariates in Plink
0
gravatar for Laura
4.0 years ago by
Laura20
UFRGS, Brazil
Laura20 wrote:

I'm performing a logistic regression in Plink in a gwas data. I have age, sex and race as covariates. Should I use them as dummy categories (age and race)?

logistic plink • 1.6k views
ADD COMMENTlink modified 4.0 years ago by Floris Brenk970 • written 4.0 years ago by Laura20
0
gravatar for Floris Brenk
4.0 years ago by
Floris Brenk970
USA
Floris Brenk970 wrote:

Usually people use them 0 or 1 coded, but this also depends on the number of races you have? For age this depends on the phenotype you have.. For example when you have an age related phenotype like Alzheimer's then you just use age as a continuous covariate. Overall, it might also be good to add the first 6 or 10 (depending on your data) or so MDS dimensions of your genotype data to correct for population stratification.

ADD COMMENTlink written 4.0 years ago by Floris Brenk970
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