Question: iso-miRNA targeted mRNA
0
gravatar for ti&te
3.6 years ago by
ti&te20
ti&te20 wrote:

Dear all,

we did small RNA sequencing and now we are analysisng our data. Does anyone know any tool, script or software for iso-miRNA - Gene(mRNA) target prediction? I know that for mature miRNAs there are mirWalk, mirDB and other, but I don't find it for isoforms....

Thank you for your help...

rna-seq • 981 views
ADD COMMENTlink modified 3.5 years ago by Lars Juhl Jensen11k • written 3.6 years ago by ti&te20
1
gravatar for Lars Juhl Jensen
3.5 years ago by
Copenhagen, Denmark
Lars Juhl Jensen11k wrote:

Considering that the functional entity that targets other genes is the mature miRNA and that iso-miRNAs give rise to identical mature miRNAs, I cannot see how you would define different targets for them. In my opinion, the sensible way to perform the analysis is to predict targets for the mature miRNAs and, if necessary, assign all iso-miRNAs with the targets of their respective mature miRNA.

ADD COMMENTlink written 3.5 years ago by Lars Juhl Jensen11k
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