Forum: Segmentation method comparisons: HMM, CBS, RS
1
gravatar for Shicheng Guo
11 months ago by
Shicheng Guo4.6k
Shicheng Guo4.6k wrote:

Hi All,

Segmentation processing is quite important in CNV and DMR analysis. However, is there any paper to compare the power for the difference methods? How many Segmentation method could be applied? I only know HMM, CBS, Rank Segmentation, is there any other popular methods?

Regards,

segmentation cbs forum hmm rank • 447 views
ADD COMMENTlink modified 10 months ago by Aerval240 • written 11 months ago by Shicheng Guo4.6k
1
gravatar for Aerval
10 months ago by
Aerval240
Germany
Aerval240 wrote:

Well, DSS only looks for consecutive CpGs which reach a certain p-value, though thats also a HMM to some degree.

The review I have most of my information from is Robinoson et al. 2014: (Statistical methods for detecting differentially methylated loci and regions). If you have more I would also be interested.

ADD COMMENTlink written 10 months ago by Aerval240
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1009 users visited in the last hour