Forum: Segmentation method comparisons: HMM, CBS, RS
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gravatar for Shicheng Guo
10 weeks ago by
Shicheng Guo4.2k
Shicheng Guo4.2k wrote:

Hi All,

Segmentation processing is quite important in CNV and DMR analysis. However, is there any paper to compare the power for the difference methods? How many Segmentation method could be applied? I only know HMM, CBS, Rank Segmentation, is there any other popular methods?

Regards,

segmentation cbs forum hmm rank • 206 views
ADD COMMENTlink modified 8 weeks ago by Aerval220 • written 10 weeks ago by Shicheng Guo4.2k
1
gravatar for Aerval
8 weeks ago by
Aerval220
Germany
Aerval220 wrote:

Well, DSS only looks for consecutive CpGs which reach a certain p-value, though thats also a HMM to some degree.

The review I have most of my information from is Robinoson et al. 2014: (Statistical methods for detecting differentially methylated loci and regions). If you have more I would also be interested.

ADD COMMENTlink written 8 weeks ago by Aerval220
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