Question: Correct GC bias using read counts and Loess regression method
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gravatar for fatima.m.zare
2.1 years ago by
fatima.m.zare20 wrote:

I read this post ( C: Compute Binned Gc-Normalized Read Counts From Bam File ) and I am wondering how can I remove GC content bias with Loess regression?

ADD COMMENTlink written 2.1 years ago by fatima.m.zare20

If you have an issue with GC-bias, why not use computeGCBias and correctGCBias from deepTools?

ADD REPLYlink written 2.1 years ago by Devon Ryan88k

Actually I want write my own code. I want to know about the method that use loess output and do correction for read counts. but Thanks for your answer. I will look at them maybe I can find their methods.

ADD REPLYlink written 2.1 years ago by fatima.m.zare20
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