I am working on a GWAS project, and I wanted to estimate the gain in power that I get by using a quantitative variable instead of a categorical.
I have already run the GWAS analysis for my quantitative variable. If I where to "transform" it into a categorical one, say by binning it, and run the GWAS, is there a way to estimate the gain in power? Can I do that using my data? Or would it be better to try to run some sort of simulation?
I think a way to visualize the difference would be doing a QQ-plot? Also I could compare the P-values distribution, but since there are not normal what would be the best way?