From co-fractionation experiments we've identified a subset of known mammalian protein complexes as interesting, approximately 50 CORUM complexes. We'd like to do an enrichment-style analysis to know more about them. One question I have is whether these complexes are particularly stable (since stable complexes should be biased towards detection). However I don't know how to approach finding the stability of a protein complex.
Given a list of proteins in a complex, are there any conventional, in silico ways to estimate the stability of that protein complex? If not, have people published numbers for the stability of well-known complexes?
I'm okay being vague about the definition of "stability" since I'll be satisfied with an answer that uses any definition of it.
(This question was originally asked on biology.stackexchange but didn't get an answer.)