MEME vs. HOMER for de novo and known Motif finding
Entering edit mode
5.3 years ago
rbronste ▴ 400

Hi everyone,

Just wanted to see about a general consensus for how folks are doing motif finding for both ChIP-seq and chromatin accessibility assays. A combo of the two followed by intersection? Asking because of myriad nebulous datasets their motif assumptions are based on. Seems to be considerable overlap and redundancy, especially when dealing with families of TFs between human and model organisms etc. Wanted to get an idea of how people like to approach this. Thank you.

meme ChIP-Seq HOMER motif • 3.3k views

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