After reading the paper and docs, I am having a little trouble understanding the difference and usage for calling at the segment level or the bin level. I am running CNVkit using human exome seq data.
My questions are:
What use case would the segment level calls be best for
What use case would the bin level calls be best for
Which one is more accurate in what context
What is the point of having two? Is the bin level output noisier but at a higher resolution than the segment level? Just assuming default segmentation and bin sizes. I'm really confused here -- anything helps!