I have an excel spreadsheet I'm trying convert to VCF File. I've got most fields right but I can't figure out how to convert to homologous / heterogeneous SNPs to one of these:
What is the difference between these?
- 1/0 vs 0/1 ?? (I'm guessing no difference ???)
- 1/1 vs 0/0 ??
- 0|1 vs 0/1 ?? (1st method is haplotype specific, 2nd method is not? No linkage?)
I'm trying to read the manual but it's greek to me. Any help?
This is my input
Current version of handmade VCF