Question: How should I choose? Decoy or not?
0
gravatar for SmallChess
2.9 years ago by
SmallChess500
Australia
SmallChess500 wrote:

Whe I goto: ftp://ftp.broadinstitute.org/bundle/b37/, there are two FASTA files I can use for alignment:

  • human_g1k_v37_decoy.fasta.gz
  • human_g1k_v37.fasta.gz

The two files are very close in file size. As far as I understand, the decoy version is slighter faster. Other than that, anything else I should consider?

I have a human sample, how should I choose? Speed is not a particular concern for me.

genome • 917 views
ADD COMMENTlink modified 2.9 years ago • written 2.9 years ago by SmallChess500
4
gravatar for h.mon
2.9 years ago by
h.mon29k
Brazil
h.mon29k wrote:

Oddly, I get an error 550: no such file or directory when trying to reach ftp://ftp.broadinstitute.org/bundle/b37/. Anyway, here (at "Which version should I use?") you will find a short explanation about the decoy genome, and here, a longer explanation.

ADD COMMENTlink modified 2.9 years ago • written 2.9 years ago by h.mon29k
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