Coverage definition in SPAdes
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7.0 years ago
sridhar56 ▴ 110

I am trying to understand what the coverage definition mean in SPAdes.

According to SPAdes, this is what they say:

"Read coverage cutoff value. Must be a positive float value, or 'auto', or 'off'. Default value is 'off'. When set to 'auto' SPAdes automatically computes coverage threshold using conservative strategy."

How does SPAdes calculate the auto coverage. I could not find any information regarding the conservative strategy. Kindly help.

next-gen Assembly sequencing • 2.0k views
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