Question: Multiple Sequence Alignement
0
gravatar for pradeep13march
2.6 years ago by
pradeep13march0 wrote:

Hello i want to know that generally for find protein conserve domain by the multiple sequence alignment but for find conserve domain if first i will convert these protein into m-rna and then MSA of among these m-rna sequence. after MSA the mrna region which will we be conserve in result, can be use these conserve mrna sequence for modelling a protein.

Thank you

virus alignment sequence domain • 774 views
ADD COMMENTlink modified 2.6 years ago • written 2.6 years ago by pradeep13march0

Hi, it is not clear what you are asking. Please take your time to reformulate your question using standard english.

ADD REPLYlink written 2.6 years ago by Michael Dondrup46k

sir i want to know that can i use mrna sequence of any proteins for find out conserve domain. (Multiple Sequence alignment ).

ADD REPLYlink written 2.6 years ago by pradeep13march0
1

Conserved regions are more likely to be found in proteins. Because of synonymous variations (mutations) in DNA/RNA you can better not use the DNA/RNA sequences but first translate it into protein sequences.

ADD REPLYlink written 2.6 years ago by Benn7.9k

if first i will convert these protein into m-rna and then MSA of among these m-rna sequence

pradeep13march : If you already have protein sequence why are you back translating that into mRNA?

Take a look at this guide before reformulating your question: How To Ask Good Questions On Technical And Scientific Forums

ADD REPLYlink modified 2.6 years ago • written 2.6 years ago by genomax74k
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