Question: Reason of excluding homolog protein in protein subcellular location prediction
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gravatar for ruhi.jamali
2.0 years ago by
ruhi.jamali0 wrote:

Hi everyone, Protein localization (subcellular localization) is an active field of research. In previously published papers on this problem, people exclude the homologous proteins from data sets. I was wondering if any body knows the reason of excluding homologous proteins?! Is it for preventing the bias of precision/recall or preventing from employing the homology information?! Thank you

ADD COMMENTlink modified 2.0 years ago by fishgolden390 • written 2.0 years ago by ruhi.jamali0
1
gravatar for fishgolden
2.0 years ago by
fishgolden390
fishgolden390 wrote:

It depends on the steps (training or testing) that exclusion procedure were used. However, basically, it is "for preventing the bias of precision/recall or preventing from employing the homology information”. In addition, for preventing a predictor to become biased to proteins which belong to large family (many similar proteins are included in the training dataset).

ADD COMMENTlink written 2.0 years ago by fishgolden390
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