From COSMIC mutations to MAF files
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4.4 years ago
fernandov ▴ 10

Hello, I downloaded the mutation file CosmicMutantExport, containing all mutation from the mutation database COSMIC. From this file I want to discriminate driver mutations from passenger mutations using the program MutSigCV. But this program requiers a MAF file. Now, I believe that the file CosmicMutantExport have all the information needed to create a MAF file, but I don't know how to make it.

The data of CosmicMutantExport: can be checked in http://cancer.sanger.ac.uk/cosmic/download at COSMIC Mutation Data.

So, my question is, do you know a method or application to make the MAF file from CosmicMutantExport?

Any help is appreciated, thanks in advance and apologies for the english.

COSMIC MAF MutSigCV driver gene • 1.8k views
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Perhaps your question is answered here? How to use MutSigCV correctly

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thanks for the comment, but the problem in that question seems to be producing the MAF file from raw sequenced data, Am I wrong?, and in my case the data is processed and the mutations described, but in another format. So, the process seems to be different.

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