Question: From COSMIC mutations to MAF files
gravatar for fernandov
11 months ago by
fernandov0 wrote:

Hello, I downloaded the mutation file CosmicMutantExport, containing all mutation from the mutation database COSMIC. From this file I want to discriminate driver mutations from passenger mutations using the program MutSigCV. But this program requiers a MAF file. Now, I believe that the file CosmicMutantExport have all the information needed to create a MAF file, but I don't know how to make it.

The data of CosmicMutantExport: can be checked in at COSMIC Mutation Data.

So, my question is, do you know a method or application to make the MAF file from CosmicMutantExport?

Any help is appreciated, thanks in advance and apologies for the english.

mutsigcv driver gene cosmic maf • 433 views
ADD COMMENTlink modified 11 months ago • written 11 months ago by fernandov0

Perhaps your question is answered here? How to use MutSigCV correctly

ADD REPLYlink written 11 months ago by CMosychuk20

thanks for the comment, but the problem in that question seems to be producing the MAF file from raw sequenced data, Am I wrong?, and in my case the data is processed and the mutations described, but in another format. So, the process seems to be different.

ADD REPLYlink modified 11 months ago • written 11 months ago by fernandov0
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