Question: From COSMIC mutations to MAF files
0
gravatar for fernandov
6 days ago by
fernandov0
fernandov0 wrote:

Hello, I downloaded the mutation file CosmicMutantExport, containing all mutation from the mutation database COSMIC. From this file I want to discriminate driver mutations from passenger mutations using the program MutSigCV. But this program requiers a MAF file. Now, I believe that the file CosmicMutantExport have all the information needed to create a MAF file, but I don't know how to make it.

The data of CosmicMutantExport: can be checked in http://cancer.sanger.ac.uk/cosmic/download at COSMIC Mutation Data.

So, my question is, do you know a method or application to make the MAF file from CosmicMutantExport?

Any help is appreciated, thanks in advance and apologies for the english.

ADD COMMENTlink modified 4 days ago • written 6 days ago by fernandov0

Perhaps your question is answered here? How to use MutSigCV correctly

ADD REPLYlink written 6 days ago by CMosychuk0

thanks for the comment, but the problem in that question seems to be producing the MAF file from raw sequenced data, Am I wrong?, and in my case the data is processed and the mutations described, but in another format. So, the process seems to be different.

ADD REPLYlink modified 6 days ago • written 6 days ago by fernandov0
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