I am working on public genotype data in opensnp. I found that different platform (e.g., 23andme, decodeme etc) uses different genome versions (e.g., GRCh37 or GRCh36) and therefore, I have found different chromosomal position for the same reference SNP (rs#) id. For few SNP ids, I checked in dbSNP that the genotype remains the same even though the genomic position is shifted from GRCh37 to GRCh38.
My question is that if I want to infer biology (SNP association to a phynotype) from those SNPs obtained form different platforms, do I need to convert genomic position from different genome versions to one version? Or, can I use rs# to call a particular genotype independent of genome version?
Thanks in advance!