Overview:
The Gladstone Institutes is an independent, not-for-profit research organization affiliated with the University of California San Francisco (UCSF), contributing to the health and well being of all people through medical research, education, and outreach in the areas of heart disease, HIV/AIDS, and neurological disease. Gladstone Bioinformatics hosts a convergence zone of cutting edge research, omics analytics, biostatistics and technology development, and is one of the primary centers for the National Resource for Network Biology, an NIH-sponsored resource for broadly distributed network biology software and methods. We are located in an award winning building adjacent to UCSF's Mission Bay Campus.
Description:
We are seeking a talented Bioinformatician with expertise in whole genome analysis to join the dynamic bioinformatics team here at Gladstone Institutes. You will be providing bioinformatics and computational support to the world-class biomedical research conducted in labs at Gladstone Institutes, UCSF, and beyond. Working closely with experimental scientists, you will lead end-to-end studies from hypotheses and experimental design, to analysis plans, implementation and pipelining, to methods assessment and result reporting or publication. You will be working with whole genome sequence data primarily, but may work with a variety of data types generated by various platforms and technologies (eg, Bulk RNA-seq, Single-cell sequencing, ChIP-seq, ATAC-seq, metagenomics, CRISPR screens, Mass spectrometry, and others). Expertise and knowledge of state of the art sequencing tools and platforms, to variant calling, variant annotation, and sequence data manipulation is required. Experience with family- based sequence analysis and pedigree analysis would be a plus. You will have opportunities for methods development, technical writing for grant applications and manuscripts, travel for conferences, meeting presentation and further training to develop your expertise and skill sets.
Qualifications:
PhD or MS with 3+ years of working experience in Bioinformatics/Statistics (or similar fields). At least four years of experience with analysis of sequence data, large biological datasets using R, Python, Perl or equivalent is required. Statistical genetics experience or experience incorporating various biological data types is strongly preferred. Prior consulting or industrial experience supporting research is a plus. The successful candidate will have a strong background in computational science, statistical analysis, experimental design, and quantitative analysis of biological systems, as well as a demonstrated ability to communicate and work effectively with all types and levels of internal and external collaborators.
Salary: Based on experience.
Start Date: May 2017 preferred.
Application Instructions:
Please submit the following:
- CV
- Cover letter (optional)
- Contact info for 3 references (can be submitted later)
Questions:
- Do you have a PhD or M.S with 4+ years working experience in Bioinformatics/Statistics, or Computational Biology?
- Do you have at least four years of experience with programming in R or Python?
- Do you have experience working in a high-performance computing environment (e.g., cluster)?
- Do you have experience with NGS data analysis?
- Do you have experience with exome or whole genome sequencing data?
- Do you have experience working with metagenomics data?
- Do you have experience analyzing hierarchical, longitudinal or survival data?
- Are you comfortable discussing hypothesis testing, regression, and ANOVA with non-statisticians?
Apply online: https://careers-gladstone.icims.com/jobs/1328/staff-research-scientist-%28bioinformatician-statistician%29/job
