R square value from genotype imputation process
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Entering edit mode
6.9 years ago
isalinas221 ▴ 10

Hi everyone! I know this is not a bioinformatic question, but any help would be greatly apreciated!

I am currently working with imputed genotypes and I'm wondering...why lots of papers report R² >0.3 (Rsq in minimac 3 outputs) as a good imputation quality score?

I don't know, my current statistical background says that a value like that does not look very correlated to the genotyped variants whichever they are.

What do you know about it?

Thanks in advance!

GWAS Imputation Population Genetics • 1.6k views
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