We have a list of drugs that reverse a particular biological phenotype. Now we want to correlate each drug to diseases to approximate the danger of these substances.
The end result should be something like a list of pvalues(or distances..) for each drug to promote particular diseases.
Does anyone know good ways to calculate correlations from drugs to diseases?
We know about DrugVsDisease, but is there something similar or better ?
Not sure if what I am mentioning here can already somehow be achieved using the DVD package. In my own experience I think it can only be used to do drug-drug and disease-disease relationships. If this is the way to go please let me know !
We only have the drug name, so the diseaseRL data(differentially expressed genes) from the DVD package may be useful.
We would like to use R, so it is possible to select on different characteristics.
Best Regards, Rick