Question: Difference between read and contig based taxonomic classification
gravatar for BAGeno
10 months ago by
BAGeno60 wrote:


I want to understand the difference between read based and contig based classification. What is the methodology behind these two? Which is more accurate?

ADD COMMENTlink modified 10 months ago by Sej Modha2.8k • written 10 months ago by BAGeno60
gravatar for Sej Modha
10 months ago by
Sej Modha2.8k
Glasgow, UK
Sej Modha2.8k wrote:

Read based taxonomic classification is where each read generated from a sequencing method is search against a database of known sequences to find similarity. Contig are longer sequences generated by stitching overlapping reads. Contig based classification is where these longer sequences are search against known sequences to identify similarity and label them taxonomically. For both cases a number of different tools can be used to search against a set of databases. Some examples of such tools are: RiboPicker, BLAST, DIAMOND

ADD COMMENTlink written 10 months ago by Sej Modha2.8k
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