Question: WGCNA requires always a trait data?
0
gravatar for adriana.gallego.02
24 months ago by
adriana.gallego.0210 wrote:

Hi, I did an RNA-seq analysis and Im planning to analyze with WGCNA, I have seen several papers with trait data, but I have a large RNA-seq sampling but few trait data. I was wondering if it is valid just do WGCNA with the expression data.

Thanks

rna-seq wgcna • 961 views
ADD COMMENTlink modified 21 months ago by Biostar ♦♦ 20 • written 24 months ago by adriana.gallego.0210

To what end? The point of WGCNA is to use a network approach to find large groups associated with phenotypic changes.

ADD REPLYlink written 24 months ago by Devon Ryan90k

Hello adriana.gallego.02!

It appears that your post has been cross-posted to another site: https://support.bioconductor.org/p/96569/

This is typically not recommended as it runs the risk of annoying people in both communities.

ADD REPLYlink written 24 months ago by WouterDeCoster39k

This is amusing, since WGCNA isn't a bioconductor package, so it'll get 0 support on that site :P

ADD REPLYlink written 24 months ago by Devon Ryan90k
1

Although, if I'm not mistaken, the author is active there.

ADD REPLYlink written 24 months ago by WouterDeCoster39k
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