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Research Scientist (Bioinformatician)
Reference Number017606LocationGartnavel CampusCollege / ServiceCOLLEGE OF MVLSDepartmentRI CANCER SCIENCESJob FamilyResearch And TeachingPosition TypeFull TimeSalary Range£33,943 - £38,183 Job Purpose
To make a leading contribution to the translational research agenda of the Paul O'Gorman Leukaemia Research Centre (POG-LRC), using genomics and other -omics data (particularly RNA-seq data) to investigate molecular mechanisms of leukaemia and provide integrated clinical information for therapeutic development of precision medicine; To conduct, assist and publish research in the area of leukaemia stem cell biology and systems biology under the direction of the Head, Haemato-oncology/systems medicine Group (Dr Xu Huang).
Main Duties and Responsibilities
Perform the following activities in conjunction with the Principal Investigator (PI):
Assist and contribute to the planning and conduct of assigned research individually or jointly in accordance with the project deliverables and POG-LRC and Institute of Cancer Sciences (ICS) research strategy.
Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.
Establish and maintain your research profile and reputation and that of the POG-LRC and ICS including establishing and sustaining a track record of independent and joint publications of international quality in high profile/quality refereed journals and conferences, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem.
Survey the research literature and environment, understand the research challenges associated with the project & subject area, & develop/implement a suitable research strategy.
To contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile.
To contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research.
To develop and maintain collaborations with colleagues across the POG-LRC and ICS as well as the wider community (eg academic and Industrial Partners).
To contribute to team/group meetings/seminars/workshops and Institute research group activities to enhance the wider knowledge, outputs and culture of POG-LRC and ICS.
Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development.
Perform administrative tasks related to the activities of the research group and Institute, including budgets/expenditure.
Make a leading contribution to outreach and recruitment activities of the University of Glasgow.
If appropriate, carry out modest teaching activities (e.g. research student supervision) and associated administration as assigned by the Directors of POG-LRC and ICS and in consultation with the Head, Haemato-oncology/systems medicine Group.
Be responsible for safety management related to the organisation and running of laboratory and/or experimental techniques, equipment and processes as appropriate.
Keep up to date with current knowledge and recent advances in the field/discipline.
Engage in personal, professional and career development, to enhance both specialist and transferable skills in accordance with desired career trajectory.
Undertake any other duties of equivalent standing as assigned by Directors POG-LRC or ICS, or the Head, Haemato-oncology/systems medicine Group.
For appointment at Grade 7:
Perform the above duties with a higher degree of independence, leadership and responsibility, particularly in relation to planning, funding, collaborating and publishing research and mentoring colleagues.
Establish and sustain a track record of independent and joint published research to establish and maintain your expert reputation in the subject area.
Survey the research literature and environment, understand the research challenges associated with the project and subject area, and develop/implement a suitable research strategy.
These key tasks are not intended to be exhaustive but simply highlight several major tasks which the staff member may be reasonably expected to perform. Knowledge, Qualifications, Skills and Experience
Knowledge/Qualifications
Essential: A1. Degree or equivalent in bioinformatics, biostatistics or other relevant area of applied computing A2. Theoretical and practical knowledge in a research related field. A3. A comprehensive and up-to-date knowledge of the wider subject area or subject specialism. A4. Knowledge of specialist IT software.
Desirable: B1. Basic knowledge of contemporary research approaches in cancer biology and systems biology. B2. Working towards or completed PhD in bioinformatics, biostatistics or other relevant area of applied computing
For appointment at grade 7:
Essential: A5. A PhD or equivalent in bioinformatics, biostatistics or other relevant area of applied computing. A6. Extensive theoretical and practical knowledge of research-related field. Desirable: B3. Extensive and up-to-date theoretical and practical knowledge in genomics or systems biology or other areas related to the field of research. B4. Understanding of biostatistics, particularly with relevance to dealing with large datasets, or understanding of systems biology and approaches to integrating diverse -omic datasets.
Skills
Essential: C1. Ability to process and analyse raw genomics data, particularly RNA-seq data. C2. Research creativity and strong cross-discipline collaborative ability as appropriate. C3. Highly motivated, ability to use initiative and quick to learn new techniques. C4. Excellent communication skills (oral and written), including public presentations and ability to communicate complex concepts clearly and concisely. C5. Excellent interpersonal skills including team working and a collegiate approach. C6. Willingness and aptitude to work in a multidisciplinary environment. C7. Appropriate workload and time management skills, including a flexible approach and ability to quickly adapt to a rapidly-evolving research environment. C8. Extensive IT and data analysis/interpretation skills as appropriate. C9. Problem solving skills including a flexible and pragmatic approach.
Desirable: D1. Demonstrable ability to facilitate and/or manage a -omics project through to completion (e.g. track record of publications in relevant research area).
Experience
Essential: E1. Relevant research experience in a similar role E2. Experience in high-level programming languages (R, Python or similar) E3. Experience of -omics data handling and curation.
For appointment at grade 7: Essential: E4. Relevant research experience normally including postdoctoral experience in a related field. E5. Experience in developing pipelines or algorithms for analysing genomic sequencing data. E6. Ability to demonstrate a degree of initiative and independence as illustrated by identification of project objectives from assessment of the literature, design & analysis of experiments & drafting of papers. E7. Experience in undertaking independent research as an individual or as part of a team.
Desirable: F1. Extensive experience in dealing with large datasets and integrating diverse -omics datasets. F2. A track record of presentation and publication of research results in quality journals/conferences. F3. Experience in management of large datasets, i.e. daily backup and storage. F4. Experience of processing and analysing single cell sequencing data.
Job Features
Dimensions To carry out a range of research activities and functions within academic environments of the highest national or international quality. Publish and seek funding as appropriate to subject specialism within agreed timescales. Informal supervision and support of less experienced members of the project team e.g. postgraduate and project students. Undertake teaching or other duties in accordance with Institute policy. Engage in personal, professional and career development to enhance both specialist and transferable skills in accordance with desired career trajectory. Leadership in the design and implementation in your specific research project(s) as appropriate.
Planning and Organising Management of time and prioritisation of research, teaching and administrative duties. Planning, organisation and implementation of research project on a weekly and monthly basis. Plan research directions that are within the available budget. React to varying project needs and deadlines.
Decision Making Undertake decision making on all aspects of research project/activities. Prioritise own, and where appropriate delegate to junior team members workload. Decide on research directions and goals within remit of original project proposal. Adjust research approaches to meet project outcomes. Identify best journals for publication and meetings/conferences to attend. Purchase of equipment and materials. Safe and effective lab management.
Internal/External Relationships University colleagues: to exchange information to ensure efficient working and to facilitate cross disciplinary working. External bodies/collaborators: proactively maintain co-operation and links at all levels to enhance profile and reputation. Dissemination: preparation and presentation of reports/results and participation in meetings and conference calls.
Problem Solving Research including technical and theoretical aspects, problem solving and development of novel ideas. Awareness of project and budgetary issues and equipment lead times. Assistance of undergraduate/postgraduate students and junior team members with problems relating to research project.
Other Representation of the University/College/ through presentation at national and international events. Attendance at training events to learn and implement new research technologies. Prepared to travel to work in the UK/Europe and elsewhere as required by the University.
Friends of Paul O'Gorman funded research position A central ethos of the principal investigators at the Paul O'Gorman Leukaemia Research Centre, and the University of Glasgow, is to invest in the development of scientists for the future. Through the hard work and loyalty of hundreds of people that have raised funds for the research effort within our Centre, we are able to recruit a talented scientist to join our leukaemia research within our state-of-the-art facilities at the Paul O'Gorman Leukaemia Research Centre led by Professor Tessa Holyoake. This post represents our fastforward research strategy, that integrates innovative multidisciplinary approaches to establish a systems biology platform for "leukomics" research and future precision medicine development. The successful candidate will be part of a specialised bioinformatics team providing essential support to all existing research groups within POG-LRC, including -omics data handling, analysis and management/storage.
For informal enquiries please contact Dr Xu Huang (xu.huang@glasgow.ac.uk) Standard Terms & Conditions
Salary will be on the University's Research and Teaching Grade, level 6/7, £27,629 - £31,076/£33,943 - £38,183 per annum. This post has funding for up to 3 years in the first instance.
New entrants to the University will be required to serve a probationary period of 6 months.
The successful applicant will be eligible to join the Universities' Superannuation Scheme. Further information regarding the scheme is available from the Superannuation Officer, who is also prepared to advise on questions relating to the transfer of Superannuation benefits.
All research and related activities, including grants, donations, clinical trials, contract research, consultancy and commercialisation are required to be managed through the University's relevant processes (e.g. contractual and financial), in accordance with the University Court's policies.
It is the University of Glasgow's mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.
We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equity..
The University of Glasgow, charity number SC004401.
For informal enquiries please contact Dr Xu Huang (xu.huang@glasgow.ac.uk)
Vacancy reference: 017606 Closing date: 28 June 2017
