Hello, I have a dataset of mutations which consists of information about gene, CDS mutation, sample and AA mutation. I was wondering if there are tools to annotate this kind of data? Is it possible to convert this to vcf at all? or is there an easier way to generate consensus sequences based on this data?
This is how the file looks like
Gene_Name Sample_Name CDS_Mutation AA_Mutation 39340 05-165O c.71C>T p.T24I A1BG 06-134H1 c.330G>A p.L110L A1BG TCGA-CH-5752-01 c.480G>A p.E160E A1BG TCGA-EJ-5499-01 c.733C>T p.R245C