Im interested to hear peoples thoughts on the issues generated from this recent highly publicised nature methods paper regarding off target effects of CRISPR editing. This follow up blog by Gaetan Burio of JCSMR in Australia has some interesting insights.
Thanks all. Kenneth
Update: This paper is now being considered for retraction according to this editorial note. The Scientist has just reported criticisms of the paper also, and the article appears with a critical comment on pubmed.