Applications are invited for the post of a Post-doctoral Bioinformatician to work on a collaborative translational research project between the groups of Dr Matthias Zilbauer (Department of Paediatrics at the University of Cambridge, UK), Dr Paul Lyons (Department of Medicine, University of Cambridge, UK) and Dr Oliver Stegle (European Bioinformatics Institute - EBI, UK).
The overall aim of this project is to apply genome wide/whole genome profiling approaches to a large, prospectively recruited human tissue sample collection in order to investigate disease pathogenesis as well as develop clinical biomarkers for patients suffering from Inflammatory Bowel Diseases (IBD). A second focus lies on elucidating the role of epigenetic mechanisms in regulating cellular function in the human intestinal tract during physiological development and disease using human organoid culture models. The selected candidate will have the opportunity to work with a group of international leaders in the field of translational research (e.g. Kraiczy et al. Mucosal Immunology 2016, Baud A et al, PLoS genetics 2017, McKinney EF et al Nature 2015) and apply cutting edge computational biology approaches to unique datasets derived from disease relevant human tissue/cell samples.
Applications are invited from researchers with a PhD and evidence of one or more first author publication in a relevant research field. We welcome applicants with diverse backgrounds including biology, biomedicine, computational biology, bioinformatics or mathematics who wish to further develop and apply their bioinformatic skills. Experience in data analysis using Bioconductor packages in R (e.g. RNA and DNA sequencing, gene regulation and expression analysis, and/or modeling) or any other programming language is desired.
For full advert, please follow this link: http://www.jobs.cam.ac.uk/job/13936/