Question: Overdispersion for single cell RNA seq experiments
0
gravatar for ly.leifels
2.8 years ago by
ly.leifels0
ly.leifels0 wrote:

How can I deal with overdispersion in single-cell RNA seq experiments? especially regarding low counts?

overdispersion scrnaseq • 1.0k views
ADD COMMENTlink modified 2.2 years ago by eric.kern13150 • written 2.8 years ago by ly.leifels0

For clustering, or differential expression, or something else entirely?

ADD REPLYlink written 2.8 years ago by Devon Ryan94k

for clustering genes into gene modules

ADD REPLYlink written 2.8 years ago by ly.leifels0
1
gravatar for eric.kern13
2.2 years ago by
eric.kern13150
United States
eric.kern13150 wrote:

What have you tried so far? One sensible solution might be to try:

If those don't get you to where you need to be, then where's the gap? Do you think the estimates are off, and if so, why? Or maybe you just need more reliable quantification of uncertainty?

ADD COMMENTlink written 2.2 years ago by eric.kern13150
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