Question: Mutect 2 and related vcf in TCGA
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6.8 years ago

There are 1 vcf file from the DNA sequencing available in GDC: tumor/normal. I'm a little confused about the presence of the normal SNV in this file. Is this file containing the somatic SNVs in the normal sample? why there are no SNVs with an allelic frequency>0 in the normal but =0 in the tumor?

Mutect2 TCGA GDC • 1.3k views
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