Question: Fst computation utilizing epigenetic modifications like histon modifications or methylation
gravatar for baxy
21 months ago by
baxy150 wrote:


can anybody give some advice on how to compute Fst values between populations given a set of epigenetic modifications associated to those populations. Let say I have the information on what is methylated in my genome in 4 populations (2 controls and 2 exposed to something that causes epigenetic changes - at least this is my hypothesis) How would I compute whether my control populations differ from my modified populations ? Fst? Lets just focus on methylations because once I understand the principle on how to compute Fst on this data I'll know how to apply it to other data sets. (In case of methylations do i need to first determine the differences using for example methylKit??) How to start?

What I have : I have mapped reads associated to methylated regions in my genome

Any advice ???

thank you

ADD COMMENTlink written 21 months ago by baxy150
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2486 users visited in the last hour