Alignment Score caveats
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Entering edit mode
7.3 years ago
Joe 21k

I'm wondering what is the best metric to report for a multiple sequence alignment of proteins?

Currently I have the pairwise alignment scores from ClustalO, but it occurred to me the score might be sequence length dependant, making comparisons between them not valid? Does anyone know if this is the case?

If so, am I better off reporting pairwise sequence identity or something similar?

alignment • 1.4k views
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