Question: Recommended specifications for computer for NGS analysis
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gravatar for nickmarinakis92
21 months ago by
nickmarinakis920 wrote:

Hello, I would like to know about the specifications for computer for VCF file analysis (variant annotation and interpretation only) using ANNOVAR and VarAFT software. In addition, I would like to know about the server that I could use for safe data storage. Thanks

ADD COMMENTlink modified 12 months ago by Biostar ♦♦ 20 • written 21 months ago by nickmarinakis920
1
gravatar for h.mon
21 months ago by
h.mon24k
Brazil
h.mon24k wrote:

Use your university cluster / super-computer for the analyses. For storage, if is just you (as you did not mention anyone else), a couple of external hard-drives with redundant copies of your data and kept on different locations should suffice for safe storage.

Now, if my answer is completely off the mark, provide more details about your usage: volume of data, how many samples, how many users, is it a small one-person or lab project or a large collaborative effort, and so on.

ADD COMMENTlink modified 21 months ago • written 21 months ago by h.mon24k
1

Given the frequency at which I see consumer-grade disks fail, I wouldn't recommend external hard-drive as a safe storage solution. Plus it can take ages to transfer any serious amount of data to the cluster.

ADD REPLYlink written 21 months ago by Jean-Karim Heriche18k

True, that is the reason I suggested "a couple", I (hopefully) made my point clearer now.

ADD REPLYlink written 21 months ago by h.mon24k
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