**20**wrote:

Hi!

I have received a dataset from an old proteomic experiment which contain the SILAC ratio for 3834 proteins for a determined condition. I'm used to use statistical metrics as the p.value associated to a T-test to establish a cut-off for the consequent over-representation analysis, however, this ratio is not accompanied by any type of statistic. I got 3 technihcal replicants.

I'm wondering if exists a method to establish a statistic to this collection of ratios and the librarie/package/software to make it. References would be appreciated

Thank you!