I'd like to perform an experimental design for DESeq2 package using the LRT Test.
I've already done it before using two different conditions Treated (T) vs Untreated (U), each at different time points.
I was wondering how to design an experiment having the U replicates just at time point 0 and T replicated samples at different time-points.
Is it possible to perform it with DESeq2? I'm not able to find examples as in this special case, but i'm able to find several time-course data designed in this way.