My work focus on analysis of genomes (including human) to discover new motifs and clustering them. The clustering step alone takes a huge amount processing power. I estimate that clustering step, alone, will take approximately 2 months using my current computer (all 4 cores loaded, i5 4670K@4.1Ghz with 8 GB Ram).
Because it is such a long time to lock my computer down I couldnt actually complete it yet. I will also need more RAM but I can not estimate the peak memory requirement until I actually complete it.
Fortunately I recieved approx. 4K dollars of funding for building a workstation. And that is why I need some help.
I rather go with faster and multiple core cpus and the new AMD chip 1950X is within an acceptible price range. Also supports 8 quad-channel Ram sticks with up to 3600 MHz speed.
However, I hear so much about ECC (Error Correcting Code) Ram and how it is essential for workstations. On the other hand, unfortunately, ECC Rams are more expensive and slower than non-ECC Ram. There are UDIMM ECCs and LRDIMM ECCs both with only up to 2133 MHz speed and only dual-channel capability (at least according to what I read). 1950X will support only UDIMM ECCs according to the manufacturer and max ECC UDIMM I can get my hands on is 16 GB versions.
If I insist to go with ECC, then (1) either I have to get ECC UDIMMs at 2133 MHz speed with dual channel capacity and use it with 1950X.
(2) Or I can decide to get a server CPU such as Intel E5-2630v4 or AMD EPYC 7301, which are in my price range. However, according to the product details the aggregate CPU frequency (cpu frequency x core count) of these cpus will be significantly lower than 1950X.
(E5-2630v4= 20coresx3.1Ghz vs Epyc 7301= 32x2.7GHz vs 1950X= 32x4GHz)
On the other hand, a dual-socket server motherboard will have the potential for upgrade with a second CPU and additional Ram sticks in the future.
(3) If I choose to let go of ECC, then I can get Ram sticks with more capacity and higher speed.
So my questions are,
Is ECC so crucial for type of bioinformatics I do? If so which route should I take (1), or (2)...or any other suggestions?