Question: Edit bam files using Pysam
0
gravatar for zaidnab
8 days ago by
zaidnab0
zaidnab0 wrote:

Hi there! I am trying to edit values in a bam file, using Pysam, or any other interface. I want to change the base quality, and the read sequence of certain reads. I have searched a ton, but have not found any methods of editing bam files directly. I am not sure if this is possible. Any help would be appreciated! Thanks :)

ADD COMMENTlink modified 8 days ago by Devon Ryan70k • written 8 days ago by zaidnab0

Out of curiosity, why do you want to do that?

ADD REPLYlink written 8 days ago by ATPoint700
1
gravatar for Devon Ryan
8 days ago by
Devon Ryan70k
Freiburg, Germany
Devon Ryan70k wrote:

You can't really edit a BAM file directly, but you can iterate over the reads and write them in a modified state to a new file.

ADD COMMENTlink written 8 days ago by Devon Ryan70k
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