Question: selection pressure results by MEGA
gravatar for saima.sam717
3.1 years ago by
saima.sam71720 wrote:

Hello everyone,

I used codon based z test of selection to check selection pressure on a protein and i performed neutral test, positive test, and purifying test. Results of three different tests gave probability and static values which conflict with each other. I want to understand how to interpret results either statistically or biologically??

                           p                 statistic
Neutral test               0.348              -0.942
Positive test              1                  -0.979
Purifying test             0.161              -0.996

significance level = 0.05

Biologically i interpret that dn-ds (statistic) value is negative that means more synonyms changes so negative selection pressure. But if i look statistically every test has greater p value than 0.05 and z value is also in acceptance region for every test so on that basis every test hypothesis is accepted. that is very confusing. Please guide me if I am going in the right direction.

ADD COMMENTlink modified 3.1 years ago • written 3.1 years ago by saima.sam71720
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1310 users visited in the last hour