What tools can be used for analysis of structural variants in targeted sequencing data?
1
0
Entering edit mode
4.4 years ago
mittu1602 ▴ 180

What are possible tools that can be used for analysis of structural variants and easy to interpret in targeted sequencing data approach without providing control samples (Human samples) ?

Thank you.

SNP CNV SNV Targeted sequencing ngs • 1.3k views
ADD COMMENT
0
Entering edit mode

pindel might be worth a look, though I don't know how well it works for targeted sequencing data. Think it's meant more for whole genome analysis.

ADD REPLY
0
Entering edit mode
4.4 years ago
Sparrow_kop ▴ 240

Hi, I recently also conduct the SV analysis of target sequencing. From my own experience, I think you can try manta, a very sensitive and high performance tool which also under active maintain. Also It can analysis single sample without control sample, you can refer the manual.

ADD COMMENT

Login before adding your answer.

Traffic: 2477 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6