Closed:DESeq2 R package to perform RNAseq analysis

Question

[MAPK]

Hi Everyone, I have 3 different samples (Sample_A, Sample_B and Sample_C) and two replicates for each. So the data matrix I have contains six different columns of fold counts for Sample_A1, Sample_A2, Sample_B1, Sample_B2, Sample_C1, Sample_C2. I want to know how I can use DESeq2 tool for this data matrix and do my RNAseq analysis. Can someone please clarify. Thanks.