Hi,
I'm interested in studying the chromatin conformation for some cells in mouse. I have performed the Hi-C analysis using HiCExplorer to identify TADs and boundaries. Now, I would like to create a dataframe of bins and some value that I could compare and identify cell-specific TADs. I was thinking about using the output of hicFindTADs TAD_score, however the output produces a tab-delimited file with chr, start, end, and other 2 or 3 colums. What I understood is that the first column after the bin position is the z-score of that bin, but how about the other 1 or 2? And why in 10kb has 3 columns and for lower resolutions I have 1 column less?
Thank you in advance for any information.
Eijy