I have to annotate a list of SNPs with information about transcription factor binding sites and histone marks. I found data for download on the UCSC webpage, but I'm hoping for a more straightforward way to do this. In another post someone recommended using the Enseml VEP for this task. Is the VEP the best way to do this? Would the outcome be very different from the UCSC annotation?
When trying VEP I found "TF_binding_site" entries and "open_chromatin_region" entries in the output list. Is there any more information about histone marks that I missed? Do I have to select some additional tools for the query that I missed?
Thank you for your help!