I would like to ask you for two suggestions:
If got an incredible amount of miRNA-Seq data. Can anybody of you recommend a pipline for quality-control and alignment?
I would like to compute the tumor purity from whole gnome seq tumor (with matching control) data. I know that it is hard to get the tumor purity in silico, but I would like to incorporate this information in an analysis pipline I am developing. I "googled" some tools, but I could not find any reports from users concerning the performance. Does anyone of you have a recommendation?
Thanks and best wishes,