Question: Data analysis using statistics
gravatar for sharmatina189059
20 months ago by
United States
sharmatina18905930 wrote:

Dear all I have some data of clinical isolates (bacteria). The data contains antibiotic name, isolate name, protein id against which its shows resistance and rate of resistance for strains of that clinical isolates. the data is like this and protein is in plasmid or chromosome.

vancomycin ecoli enzA 82%resistance rate, tested for 89 strains plasmid mediated chloroamphenicol E tnz 62%resistance rate, tested for 89 strains chromosome mediated

i want to calculate whether the resistance is increasing due to plasmid or chromosome.. Can anyone suggest me the statistical procedure to calculate it? What methods can be used for this purpose?

statistics gene • 443 views
ADD COMMENTlink modified 20 months ago by Jean-Karim Heriche18k • written 20 months ago by sharmatina18905930
gravatar for Jean-Karim Heriche
20 months ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche18k wrote:

A simple approach to start with would be to do a chi-squared test of association between the two conditions (i.e plasmid vs chromosome) and the number of resistant strains. Then if a more refined analysis seems warranted, look at logistic regression.

ADD COMMENTlink written 20 months ago by Jean-Karim Heriche18k
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