Question: STAR vs STAR-fusion
1
gravatar for KVC_bioinfo
20 months ago by
KVC_bioinfo380
Boston
KVC_bioinfo380 wrote:

Hello,

I am reading the STAR manual and I came across the publication for STAR-fusion. I could not understand how different they are from each other. Could someone help me understand the difference?

Thank you in advance.

#star #aligner #star-fusion • 896 views
ADD COMMENTlink modified 20 months ago by Satyajeet Khare1.3k • written 20 months ago by KVC_bioinfo380
3
gravatar for Satyajeet Khare
20 months ago by
Satyajeet Khare1.3k
Pune, India
Satyajeet Khare1.3k wrote:

STAR aligner is a splice aware aligner that aligns junction reads using a guide GTF. STAR-fusion allows identification of fusion transcripts. In many cases you get fusion transcripts due to chromosomal translocation (cancer) or trans-splicing etc. Other splice aware aligners (Tophat-Fusion) also have fusion engine for same purpose.

ADD COMMENTlink modified 20 months ago • written 20 months ago by Satyajeet Khare1.3k
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