Question: Protein sequences to where they bind to the genome
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gravatar for int11ap1
2.2 years ago by
int11ap1380
Barcelona
int11ap1380 wrote:

I have a multifasta with multiple sequence proteins. My aim is to locate the sites in the genome they bind to. Is that possible?

multialignment protein • 596 views
ADD COMMENTlink written 2.2 years ago by int11ap1380

Depends what kind of proteins you have. If they are all known transcription factors or other known DNA binders, then maybe. There are many online tools which will predict how likely your proteins are to bind DNA, or to bind particular sequences, but I doubt there is any tool that could tell you where any random protein would bind in the genome.

Also, what genome are you interested in?

ADD REPLYlink written 2.2 years ago by Joe15k

I agree. We need to know how the sequences in the multi-fasta are related. Is it the entire complement of proteins, or is it a particular subset?

ADD REPLYlink written 2.2 years ago by YaGalbi1.4k
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