A position of a Bioinformatician, at the level of Postdoctoral Scientist, has been created to carry out research on the immunological impact of endogenous retroviruses in the development and progression of cancer, using large-scale genomics and transcriptomics data. This role will be pivotal in ensuring continuation of research on immunity to exogenous and endogenous retroviruses and cancer in the Kassiotis lab. The post holder will be part of a team of researchers in the Kassiotis lab at the Francis Crick Institute. Lab web page: https://www.crick.ac.uk/george-kassiotis
KEY RESPONSIBILITIES These include but are not limited to;
• Working within a team that carries out research on immune reactivity to retroviral antigens in the context of infection and cancer. • Carrying out the processing, analysis and integration of distinct next generation sequencing and multiple ‘omics data. • Using existing, and developing and maintaining pipelines for the analysis of multiple ‘omics data.
KEY EXPERIENCE AND COMPETENCIES
The post holder should embody and demonstrate our core Crick values: bold, imaginative, open, dynamic and collegial, in addition to the following.
Essential • PhD in computational biology, computer science, or biology • A strong background in statistical analyses • Experience in the analysis of next generation sequencing data • Experience with scripting language (Python or Perl), R statistical programming language, Bioconductor, and with LINUX based systems • Ability to design and maintain analysis pipelines • The post holder is expected to be creative and motivated, conscientious and able to work independently, but also to interact well within the team • Excellent record keeping and ability to communicate well in English are also essential
• Demonstration of scientific ability and excellence by means of authorship (first author) peer reviewed publications in internationally recognized scientific journals
Desirable • Experience in bioinformatics analysis of repetitive elements • Experience in bioinformatics analysis of T cell receptor repertoires
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases. An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London. The Crick was formed in 2015, and in 2016 it moved into a brand new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one roof in Europe. The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; to developing emerging talent and exporting it the rest of the UK; to public engagement; and to helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
To apply please click on https://goo.gl/YhJYK9