i have a list of microRNA (almost 300) for which i have raw counts in control and a stress condition for 2 genotypes. I was thinking to use the absolute values (after normalization) for a network construction for each genotype in the 2 conditions (stress and control) and compare these networks in order to find conserved modules between the genotypes.
Furthermore i would like to insert in some way the data i have from a target prediction analysis. But i have no RNA-seq data for the mRNA.
Any ideas or suggestion for facing these steps? Every tip (papers, softwares, guidelines) would be much appreciated