Question: Differential expression analysis tool for single cell RNA-seq data
0
gravatar for tunl
9 months ago by
tunl50
tunl50 wrote:

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

ADD COMMENTlink modified 9 months ago by theobroma221.1k • written 9 months ago by tunl50
2
gravatar for lessismore
9 months ago by
lessismore490
Mexico
lessismore490 wrote:

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

ADD COMMENTlink written 9 months ago by lessismore490

This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

ADD REPLYlink written 9 months ago by tunl50
1
gravatar for theobroma22
9 months ago by
theobroma221.1k
theobroma221.1k wrote:

You can also search the RNA-seq blog:

http://www.rna-seqblog.com/powsimr-power-analysis-for-bulk-and-single-cell-rna-seq-experiments/?utm_source=RNA-Seq+Blog+Subscribers&utm_campaign=584ab32450-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_e9607034ee-584ab32450-76527253

ADD COMMENTlink written 9 months ago by theobroma221.1k

Thanks so much for the information!

ADD REPLYlink written 9 months ago by tunl50
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1643 users visited in the last hour