Question: Differential expression analysis tool for single cell RNA-seq data
0
gravatar for tunl
12 months ago by
tunl50
tunl50 wrote:

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

ADD COMMENTlink modified 12 months ago by theobroma221.1k • written 12 months ago by tunl50
2
gravatar for lessismore
12 months ago by
lessismore510
Mexico
lessismore510 wrote:

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

ADD COMMENTlink written 12 months ago by lessismore510

This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

ADD REPLYlink written 12 months ago by tunl50
1
gravatar for theobroma22
12 months ago by
theobroma221.1k
theobroma221.1k wrote:

You can also search the RNA-seq blog:

http://www.rna-seqblog.com/powsimr-power-analysis-for-bulk-and-single-cell-rna-seq-experiments/?utm_source=RNA-Seq+Blog+Subscribers&utm_campaign=584ab32450-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_e9607034ee-584ab32450-76527253

ADD COMMENTlink written 12 months ago by theobroma221.1k

Thanks so much for the information!

ADD REPLYlink written 12 months ago by tunl50
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