Question: Differential expression analysis tool for single cell RNA-seq data
0
gravatar for tunl
4 weeks ago by
tunl40
tunl40 wrote:

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

ADD COMMENTlink modified 4 weeks ago by theobroma221.0k • written 4 weeks ago by tunl40
2
gravatar for lessismore
4 weeks ago by
lessismore370
Mexico
lessismore370 wrote:

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

ADD COMMENTlink written 4 weeks ago by lessismore370

This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

ADD REPLYlink written 4 weeks ago by tunl40
1
gravatar for theobroma22
4 weeks ago by
theobroma221.0k
theobroma221.0k wrote:

You can also search the RNA-seq blog:

http://www.rna-seqblog.com/powsimr-power-analysis-for-bulk-and-single-cell-rna-seq-experiments/?utm_source=RNA-Seq+Blog+Subscribers&utm_campaign=584ab32450-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_e9607034ee-584ab32450-76527253

ADD COMMENTlink written 4 weeks ago by theobroma221.0k

Thanks so much for the information!

ADD REPLYlink written 4 weeks ago by tunl40
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