Question: Differential expression analysis tool for single cell RNA-seq data
0
gravatar for tunl
2.4 years ago by
tunl60
tunl60 wrote:

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

ADD COMMENTlink modified 2.4 years ago by theobroma221.1k • written 2.4 years ago by tunl60
2
gravatar for lessismore
2.4 years ago by
lessismore770
Mexico
lessismore770 wrote:

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

ADD COMMENTlink written 2.4 years ago by lessismore770

This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

ADD REPLYlink written 2.4 years ago by tunl60
1
gravatar for theobroma22
2.4 years ago by
theobroma221.1k
theobroma221.1k wrote:

You can also search the RNA-seq blog:

http://www.rna-seqblog.com/powsimr-power-analysis-for-bulk-and-single-cell-rna-seq-experiments/?utm_source=RNA-Seq+Blog+Subscribers

ADD COMMENTlink modified 17 months ago by Gjain5.4k • written 2.4 years ago by theobroma221.1k

Thanks so much for the information!

ADD REPLYlink written 2.4 years ago by tunl60
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