Differential expression analysis tool for single cell RNA-seq data
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5.0 years ago
tunl ▴ 70

I am looking for the best available differential expression analysis tool for single cell RNA-seq data.

From the literatures that did some comparisons, I found that MAST, ROTS, SCDE, DEGseq, D3E, and SAMseq seem to have good performance. Which one would you recommend based on your actual experience (most accurate, reliable, and stable tool)?

I’d greatly appreciate your advice.

Thank you very much!

single-cell RNA-seq DE analysis RNA-Seq • 2.9k views
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5.0 years ago
lessismore ★ 1.3k

Hey man, check this, its very fresh! >> https://hemberg-lab.github.io/scRNA.seq.course/index.html

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This is great! Thank you so much! Monocle vs. MAST, which one do you think is better? Thanks a lot!

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Thanks so much for the information!

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